Laboratory Medicine

Test Directory / DPD mutation analysis for 5-fluorouracil (5-FU) toxicity

DPD mutation analysis for 5-fluorouracil (5-FU) toxicity

EDTA

Test	DPD mutation analysis for 5-fluorouracil (5-FU) toxicity
Common Abbreviations	DPD-5FU
Profile	NA
Tube type	EDTA
Clinical Indication	Polymorphic variants in the DPYD gene are associated with severe, sometimes fatal, toxicity to fluoropyrimidine therapy.
Specimen Type	Blood
Sample type	Whole blood
Minimum Volume	3mL
Special Precautions	No special requirements
Stability	5 days at 2 - 8°C
Turnaround Time	Contact Referral Laboratory
Laboratory	Purine Research Laboratory, St Thomas' Hospital, London, SE1 7EH. 020 7188 1266
Reference Interval	Interpretation provided on report
Limitations
Notes	Please complete ViaPath request form and send with request http://www.viapath.co.uk/sites/default/files/upload/DPD-5FU%20REQUEST%20FORM.XLSX

Update for visitors

Visiting restrictions are in place at our hospitals to stop the spread of norovirus. These restrictions will be in place until further notice.

The following wards are closed to visitors:

All wards at York Hospital

Coronary Care and Ash Ward at Scarborough Hospital

There are four exceptions only to the restrictions. These are:

For patients who are receiving end of life care

Paediatric patients (babies and children)

Maternity care

The family carers of those with dementia

We understand these restrictions can be difficult when a loved one is unwell. The restrictions will be reviewed daily and lifted as soon as it is safe. Thank you for your understanding as we try to reduce the spread of norovirus in our hospitals.