Laboratory Medicine
Test Directory / Insulin-like Growth Factor 1
Insulin-like Growth Factor 1
Brown clotted serum, gel barrier or lithium heparin
| Test | Insulin-like Growth Factor 1 |
|---|---|
| Common Abbreviations | IGF1 |
| Profile | NA |
| Tube type | Brown clotted serum, gel barrier or lithium heparin |
| Clinical Indication | Insulin-like growth factor 1 (IGF1) measurement is useful in the evaluation of growth disorders and in the diagnosis and monitoring of pituitary disease. |
| Specimen Type | Blood |
| Sample type | Serum or plasma |
| Minimum Volume | 0.5mL If requesting more than 10 biochemistry tests please send an additional sample specifically for IGF1. |
| Special Precautions | No special requirements |
| Stability | 24 hours at 15 - 25°C, 48 hours at 2 - 8°C and 28 days at -20°C |
| Turnaround Time | Inpatient: 7 days Outpatient/GP: 7 days |
| Laboratory | York |
| Reference Interval | Please refer to reference ranges available: https://www.yorkhospitals.nhs.uk/our-services/a-z-of-services/lab-med/general-information/information-for-health-care-professionals1/advice-for-primary-or-secondary-care-clinical-biochemistry/ |
| Limitations | Analysis should not be performed on haemolysed, icteric or lipaemic samples. The assay is unaffected by biotin (< 205 nmol/L or < 50 ng/mL) No interference was observed from rheumatoid factors up to a concentration of 1200 IU/mL. No interference was observed from IgG < or equal to 3.3 g/dL; IgA < or equal to 0.5 g/dL; IgM < or equal to 1.0 g/dL Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration. In vitro tests were performed on 16 commonly used pharmaceuticals. No interference with the assay was found. In addition, special growth disorder drugs were tested. No interference was found. In rare cases, interference due to extremely high titres of antibodies to analyte specific antibodies, streptavidin or ruthenium can occur. These effects are minimized by suitable test design. |
| Notes |
