Laboratory Medicine
Test Directory / Progesterone
Progesterone
Brown clotted serum, gel barrier
| Test | Progesterone |
|---|---|
| Common Abbreviations | PRG |
| Profile | NA |
| Tube type | Brown clotted serum, gel barrier |
| Clinical Indication | Clinical evaluation of progesterone confirms ovulation and normal luteal function in nonpregnant women. Inadequate progesterone production by the corpus luteum may indicate luteal phase deficiency (LPD), which is associated with infertility and early miscarriage. Women using oral contraceptives have suppressed progesterone levels. |
| Specimen Type | Blood |
| Sample type | Serum |
| Minimum Volume | 0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample. |
| Special Precautions | No special requirements |
| Stability | 1 days at 20 - 25°C, 5 days at 2 - 8°C and 6 months at -20°C |
| Turnaround Time | Inpatient: 48 hours Outpatient/ GP: 48 hours |
| Laboratory | York |
| Reference Interval | Female Luteal peak: 5.8 - 75.9 nmol/L (Quoted by the manufacturer) |
| Limitations | Analysis should not be performed on haemolysed, icteric or lipaemic samples. Visibly turbid samples give a false low result. The assay is unaffected by biotin < 123 nmol/L or < 30 ng/mL. No interference was observed from rheumatoid factors up to a concentration of 1200 IU/mL. No interference was observed from IgG < 7.0 g/dL; IgA < 0.4 g/dL; IgM < 1.0 g/dL Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration. In vitro tests were performed on 16 commonly used pharmaceuticals. No interference with the assay was found. In addition, clomiphene citrate was tested. No interference was found. In rare cases, interference due to extremely high titres of antibodies to analyte specific antibodies, streptavidin or ruthenium can occur. |
| Notes |
