Laboratory Medicine
Test Directory / Conjugated Bilirubin
Conjugated Bilirubin
Brown clotted serum, gel barrier or lithium heparin
| Test | Conjugated Bilirubin |
|---|---|
| Common Abbreviations | Direct Bilirubin, Split Bilirubin, DBIL |
| Profile | NA |
| Tube type | Brown clotted serum, gel barrier or lithium heparin |
| Clinical Indication | The assessment of conjugated bilirubin is helpful in the determination of hepatic and post-hepatic jaundice. Conjugated bilirubin levels greater than 20% of total bilirubin are considered significant. Elevated conjugated bilirubin occurs in biliary tree obstruction, hepatocellular damage, cholestasis and in the inhertited conditions (Dubin-Johnson and Rotor syndrome) |
| Specimen Type | Blood |
| Sample type | Serum |
| Minimum Volume | 0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample. |
| Special Precautions | Measurement is not informative unless total biliubin is > 30umol/L |
| Stability | 2 days at 20-25°C (stored in the dark) |
| Turnaround Time | Urgent: 2 hours Inpatient: 6 hours Outpatient/ GP: 24 hours |
| Laboratory | York and Scarborough |
| Reference Interval | Interpretation provided on report |
| Limitations | Haemolysis interferes with measurement of conjugated bilirubin. Conjugated bilirubin degrades on exposure to light. Samples should be received in the lab as soon as possible after collection and stored in the dark. In very rare cases gammopathy, especially monoclonal IgM (Waldenströms macroglobulinemia), may cause unreliable results. |
| Notes |
