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Laboratory Medicine

Histology / Cellular Pathology Second Opinion and Referred samples

Second Opinion and Referred samples

Samples may need to be sent away for those cases requiring a second opinion or for tests not carried out in-house required for patient diagnosis.   The samples are sent to specialist centres or pathologists, the list below details the areas that are frequently sent referral cases.  occasionally other specialist opinions required, but these can be varied and depend upon the referring Consultant.

Second Opinions

Speciality

Referral name/location

Address

Dermatology Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Lymphoma Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Oral and Maxillofacial Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Nephrology Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Hepatology Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Urology Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Liver and GI Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Paediatric Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Gynaecological Opinion

St. James’s University Hospital

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

 

Referred Tests

Every two years an internal review is completed for referral laboratories to confirm:

  • Test/service provided
  • Accreditation status for referred tests
  • NEQAS schemes participated in and any associated poor performance,
  • Cost of services provided and their turnaround time
  • Performance characteristics
  • Sample requirements

Cytogenetic Testing

 

Postal service only.  No histology report received.

 

Regional Cytogenetic Unit

Pathology Department

St. James University Hospital

Leeds, LS9 7TF

IHC/Molecular Testing

 

BRAF mutation

EGFR

ALK IHC

ROS1 IHC

MLH promoter methylation

PD-L1 22C3/SP142

NRAS

KRAS 12C mutations

RET fusions

MET exon 14 fusions

NTRK fusions

KIT

KSHV

PIK3CA

 

The Molecular Pathology Diagnostic Service

Queen Elizabeth Hospital Birmingham

Department of Cellular Pathology

Level - 2

Queen Elizabeth Hospital Birmingham

Mindelsohn Way

Edgbaston

Birmingham, B15 2WB

 

Genomic Testing

 

BRCA

NGS

MLH/POLE

HRD

PIK3CA

NTRK

MDM2

 

North East and Yorkshire Genomic Laboratory Hub (NEYGLH)

North East & Yorkshire Genomic Laboratory Hub (NEY GLH), Central Lab Genomic Specimen Reception (Histopathology Department) Bexley Wing (Level 5) St James's University Hospital Beckett Street Leeds, LS9 7TF

Haematological Malignancies

 

Tests requested at HMDS as required to determine diagnosis.

 

Haematological Malignancy Diagnostic Service

HMDS

Level 3, Bexley Wing, St James's University Hospital. Beckett Street. Leeds LS9 7TF.

 

Amyloidosis

 

As required to determine diagnosis

 

 

National Amyloidosis Centre

University College London

Gower Street

London

WC1E 6BT

Oncotype DX testing

Genomic Health Inc

301 Penobscot Drive

Redwood City

California 94063

USA

Histopathology Reporting Service

Backlogs Ltd

 

Silvaco Technology Centre

Compass Point

St Ives

Cambridgeshire

PE27 5JL

Ophthalmology Diagnosis

 

As required to determine diagnosis.

 

Royal Hallamshire Hospital

Department of Histopathology

Glossop Rd, Broomhall, Sheffield, S10 2JF

Her-2 (gastric) and ISH testing.

 

HER-2 (gastric)

HER-2 FISH

HPV ISH

 

HSL-Advanced Diagnostics

University College London

1st Floor Rockefeller Building

21 University Street

London

WC1E 6JJ

Renal Biopsies

 

Native and renal transplant biopsies are processed at Leeds.  Three pieces of tissue sent in different fixatives for routine histology, direct immunofluorescence and electron microscopy are provided.

 

Cellular Pathology, Leeds

Department of Histopathology

Level 5, Bexley Wing

St. James’s University Hospital

Beckett Street

Leeds, LS9 7TF

Ad hoc antibodies that are not performed in-house. A full list of this can be obtained from the department if you require this information.

 

 

 

HSL-Advanced Diagnostics

Cellular Pathology

University College London

1st Floor Rockefeller Building

21 University Street

London

WC1E 6JJ

 


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