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Laboratory Medicine
Histology / Cellular Pathology Second Opinion and Referred samples
Second Opinion and Referred samples
Samples may need to be sent away for those cases requiring a second opinion or for tests not carried out in-house required for patient diagnosis. The samples are sent to specialist centres or pathologists, the list below details the areas that are frequently sent referral cases. occasionally other specialist opinions required, but these can be varied and depend upon the referring Consultant.
Second Opinions
Speciality |
Referral name/location |
Address |
Dermatology Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Lymphoma Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Oral and Maxillofacial Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Nephrology Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Hepatology Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Urology Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Liver and GI Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Paediatric Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Gynaecological Opinion |
St. James’s University Hospital |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Referred Tests
Every two years an internal review is completed for referral laboratories to confirm:
- Test/service provided
- Accreditation status for referred tests
- NEQAS schemes participated in and any associated poor performance,
- Cost of services provided and their turnaround time
- Performance characteristics
- Sample requirements
Cytogenetic Testing
Postal service only. No histology report received.
|
Regional Cytogenetic Unit |
Pathology Department St. James University Hospital Leeds, LS9 7TF |
IHC/Molecular Testing
BRAF mutation EGFR ALK IHC ROS1 IHC MLH promoter methylation PD-L1 22C3/SP142 NRAS KRAS 12C mutations RET fusions MET exon 14 fusions NTRK fusions KIT KSHV PIK3CA
|
The Molecular Pathology Diagnostic Service |
Queen Elizabeth Hospital Birmingham Department of Cellular Pathology Level - 2 Queen Elizabeth Hospital Birmingham Mindelsohn Way Edgbaston Birmingham, B15 2WB
|
Genomic Testing
BRCA NGS MLH/POLE HRD PIK3CA NTRK MDM2
|
North East and Yorkshire Genomic Laboratory Hub (NEYGLH) |
North East & Yorkshire Genomic Laboratory Hub (NEY GLH), Central Lab Genomic Specimen Reception (Histopathology Department) Bexley Wing (Level 5) St James's University Hospital Beckett Street Leeds, LS9 7TF |
Haematological Malignancies
Tests requested at HMDS as required to determine diagnosis.
|
Haematological Malignancy Diagnostic Service |
HMDS Level 3, Bexley Wing, St James's University Hospital. Beckett Street. Leeds LS9 7TF.
|
Amyloidosis
As required to determine diagnosis
|
National Amyloidosis Centre |
University College London Gower Street London WC1E 6BT |
Oncotype DX testing |
Genomic Health Inc |
301 Penobscot Drive Redwood City California 94063 USA |
Histopathology Reporting Service |
Backlogs Ltd
|
Silvaco Technology Centre Compass Point St Ives Cambridgeshire PE27 5JL |
Ophthalmology Diagnosis
As required to determine diagnosis.
|
Royal Hallamshire Hospital |
Department of Histopathology Glossop Rd, Broomhall, Sheffield, S10 2JF |
Her-2 (gastric) and ISH testing.
HER-2 (gastric) HER-2 FISH HPV ISH
|
HSL-Advanced Diagnostics |
University College London 1st Floor Rockefeller Building 21 University Street London WC1E 6JJ |
Renal Biopsies
Native and renal transplant biopsies are processed at Leeds. Three pieces of tissue sent in different fixatives for routine histology, direct immunofluorescence and electron microscopy are provided.
|
Cellular Pathology, Leeds |
Department of Histopathology Level 5, Bexley Wing St. James’s University Hospital Beckett Street Leeds, LS9 7TF |
Ad hoc antibodies that are not performed in-house. A full list of this can be obtained from the department if you require this information.
|
HSL-Advanced Diagnostics Cellular Pathology |
University College London 1st Floor Rockefeller Building 21 University Street London WC1E 6JJ |
Web page 76 published 16/04/24