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Laboratory Medicine

Test Directory / Coagulation factor VIII Inhibitors (Nijmegen)

Coagulation factor VIII Inhibitors (Nijmegen)

Citrated Plasma

TestCoagulation factor VIII Inhibitors (Nijmegen)
Common AbbreviationsBethesda / Nijmegen
Profile Coagulation Screen added on the same sample and Factor VIII assay or Refact (if on Refacto AF)
Clinical IndicationScreen and quantitation for Factor VIII inhibitor antibodies
Specimen TypeBlood
Sample TypeCitrated Plasma
Minimum Volume3 x 3 mL (adult) 3 x 1 mL (paed) (citrated plasma must be filled to bottle line)
Special PrecautionsMust write type of replacement factor product if relevant Must state if patient is on anticoagulants (DOAC, Warfarin, Heparin); known coagulation disorders; clincal symptoms (bleeding, bruising).
Stability4-6 hours
Turnaround Time24 hrs (urgent) if requested via the haematology consultants. 3 weeks (routine)
LaboratoryYork Hospital
Reference IntervalReference range printed on final report.
LimitationsHaemolysis, gross lipaemia, high haematocrit may interfere with measurement. Over or under filled samples cannot be used due to ratio between blood and citrate
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