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Laboratory Medicine

Test Directory / Coagulation factor XII assay

Coagulation factor XII assay

Citrated Plasma

TestCoagulation factor XII assay
Common Abbreviations FXII
Profile Coagulation Screen added on the same sample
Clinical IndicationTo determine if the coagulation factor XII is low or absent. Associated with reduced clot formation and bleeding. Contact Consultant Haematologist for advice.
Specimen TypeBlood
Sample TypeCitrated Plasma
Minimum Volume2 x 3 mL (adult) 2 x 1 mL (paed) (citrated plasma must be filled to bottle line)
Special PrecautionsMust state if patient is on anticoagulants (DOAC, Warfarin, Heparin); known coagulation disorders; clincal symptoms (bleeding, bruising).
Stability4-6 hours
Turnaround Time4 hours (urgent) if requested via the haematology consultants. 3 weeks (routine)
LaboratoryYork Hospital
Reference IntervalReference range printed on final report.
LimitationsHaemolysis, gross lipaemia, high haematocrit may interfere with measurement. Over or under filled samples cannot be used due to ratio between blood and citrate
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