Laboratory Medicine
Test Directory / Lupus inhibitor screen
Lupus inhibitor screen
Citrated Plasma & Brown clotted serum, gel barrier
| Test | Lupus inhibitor screen |
|---|---|
| Common Abbreviations | LIS, LUP, lupus anticoagulant |
| Profile | Must be requested with an anticardiolipin (ACA) and B2 Glycoprotein (B2GLY) or Thrombophilia Screen Antithrombin (AT), Protein C (PC), Protein S (PS) Thrombin Time (TCT), Factor V Leiden (FVL), Prothrombin Gene Mutation (F2G), Lupus Inhibitor (LIS), Anticardiolipin (ACA), B 2 Glycoprotein (B2GLY), Coagulation Screen (CLS) |
| Clinical Indication | Lupus anticoagulant testing is used to help determine the cause of an unexplained thrombosis, recurrent foetal loss, or a prolonged aPTT test. |
| Specimen Type | Blood |
| Sample Type | Citrated Plasma & Brown clotted serum, gel barrier |
| Minimum Volume | 2 x 3mL (adult) 2 x 1mL (paed) plus brown tube for ACA and B2Gly (Thrombophlia Screen requires:3 x 3mL (adult) 4 x 1mL (paed) and 1 x 0.5 - 1.0 mL brown serum for ACA & B2GLY (citrated plasma must be filled to bottle line) |
| Special Precautions | Cannot be perform if on DOAC's and Warfarin. |
| Stability | 4-6 hours |
| Turnaround Time | Urgent samples can be completed in 4 hours if requested via the haematology consultants. 3 - 6 weeks (routine) |
| Laboratory | York Hospital |
| Reference Interval | Reference range printed on final report. |
| Limitations | Haemolysis, gross lipaemia, high haematocrit may interfere with measurement. Over or under filled samples cannot be used due to ratio between blood and citrate |
| Additional Information |
