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Laboratory Medicine

Test Directory / Platelet aggregation (platelet function)

Platelet aggregation (platelet function)

Citrated Plasma

TestPlatelet aggregation (platelet function)
Common AbbreviationsPAGT
ProfilePlatelet Function Investigation PFA-100, platelt aggregration, platelet glycoproteins,platelet nucleotides
Clinical IndicationAn evaluation of patients with abnormal bleeding requires objective clinical asssessment of bleeding, history, family history and physicalexamination. After initial lab invesitgatin, further testing, such as specific bleeding disorder tests may be necessary to identify an inherited disorder or acquired condition as the cause of the dysfunction. Platelet aggregation tests the aggregation of platelet towards a panel of agonists.
Specimen TypeBlood
Sample TypeCitrated Plasma
Minimum Volume1 x 3mL (adult) 1 x 1mL (paed) (Platelet fucntion Investigation requires: 5 x 3mL (adult), 6 x 1mL (paed) (citrated plasma must be filled to bottle line)
Special PrecautionsPlease discuss with Consultant Haematologists in the first instance. Must be prearranged with Haemophilia Nurse prior to appointment and samples taken. Hand delivery to the Coagulation Lab before 10am
Stability4 hrs (unspun)
Turnaround Time2-3 days (Full platelet function investigation report available 28 days)
LaboratorySLM Haematology Laboratory Leeds St James University Hospital
Reference IntervalIssued with final report
LimitationsBy prearrangement only. Must be delivered to testing lab by 11am on day of collection. Samples must not be sent by air tube.
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