Laboratory Medicine
Test Directory / Aquaporin 4 Antibody Also known as: Neuromyelitis Optica Antibodies
Aquaporin 4 Antibody Also known as: Neuromyelitis Optica Antibodies
Brown clotted serum, gel barrier
| Test | Aquaporin 4 Antibody Also known as: Neuromyelitis Optica Antibodies |
|---|---|
| Common Abbreviations | AQ4 |
| Profile | N/A |
| Clinical Indication | Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO, or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally extensive transverse myelitis. They are infrequent in patients with optic neuritis without spinal cord involvement. |
| Specimen Type | Blood |
| Sample Type | Serum |
| Minimum Volume | 1 mL |
| Special Precautions | No special requirements |
| Stability | Contact Referral Laboratory |
| Turnaround Time | 3 weeks |
| Laboratory | Immunology Laboratory, Oxford University Hospitals NHSFT |
| Reference Interval | Contact Referral Laboratory |
| Limitations | Contact Referral Laboratory |
