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Laboratory Medicine

Test Directory / Phenytoin

Phenytoin

Brown clotted serum, gel barrier or lithium heparin

TestPhenytoin
Common AbbreviationsEpanutin, PHT
ProfileNA
Tube typeBrown clotted serum, gel barrier or lithium heparin
Clinical IndicationPhenytoin is one of the most widely prescribed anti convulsant drugs for the treatment of epilepsy particularly grand mal epilepsy, cortical focal seizures and temporal lobe epilepsy. Measured to check therapeutic levels and compliance.
Specimen TypeBlood
Sample typeSerum or plasma
Minimum Volume0.5mL If requesting more than 10 tests please send an additional brown clotted serum sample.
Special PrecautionsNo special requirements
Stability4 days at 2-25C in capped samples
Turnaround TimeInpatient: 6 hours Outpatient/ GP: 24 hours
LaboratoryYork
Reference IntervalTherapeutic Range: 5-20 mg/L (Recommended by the Pathology Harmonisation Reference Group)
LimitationsSamples containing antibodies to E. coli ?-galactosidase may result in artificially high results which will not fit the clinical profile. The incidence of patients having such antibodies is extremely low. As with any assay employing mouse antibodies, the possibility exists for interference by human anti-mouse antibodies (HAMA) in the sample, which could cause falsely elevated results.
Notes
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Maternity access at York Hospital - Saturday 22 February

On Saturday 22 February, 8am-6pm, there will be a temporary change of vehicle access to the maternity unit at York Hospital. Access via entrance 2 will be closed to allow essential works to be completed. 

If you are attending the maternity unit at York on this day, please drive in via the entrance for A&E (marked blue light priority).

The multi-storey car park will not be affected by this change, and any non-urgent visitors should continue to park in this area.